Cheng Sun

Closed-loop optical optimization enables patterned retinal stimulation in vivo at cellular scales

This paper introduces a closed-loop optical platform for precise retinal stimulation in mice, achieving high-resolution patterned stimulation with real-time focus correction.

Balancing performance and complexity of dual-wedge prism-based spectroscopic single-molecule localization microscopy

This study compares DWP-based sSMLM configurations to balance localization and spectral precision with experimental complexity.

Simultaneous regeneration of skin and bone in full-thickness cranial composite defects

This paper develops a 3D-printed composite scaffold that simultaneously regenerates skin and bone in cranial defects, achieving outcomes comparable to autografts and reducing surgical complexity.

Maximizing photon utilization in spectroscopic single-molecule localization microscopy using symmetrically dispersed dual-wedge prisms

This paper introduces a symmetrically dispersed dual-wedge prism design for spectroscopic single-molecule localization microscopy, improving lateral and spectral precision.

Volumetric montaging of optical coherence tomography in human retinas

This paper introduces a method to increase the field of view in clinical OCT by volumetrically montaging multiple datasets, achieving ultrawide FOV imaging without hardware changes.

Machine-learning-based automated Schlemms canal volumetric segmentation for optical coherence tomography

This paper introduces SC-LSS, an automated tool for volumetric segmentation of Schlemms Canal in OCT images, showing high agreement with manual segmentation and detecting changes in SC size under different intraocular pressure conditions.

Robotic Visible-Light Optical Coherence Tomography Visualizes Segmental Schlemms Canal Anatomy and Segmental Pilocarpine Response

This paper uses robotic visible-light OCT to visualize segmental Schlemms canal anatomy and its response to pilocarpine in mice, showing segmental changes in volume.

Implementation and calibration of spectroscopic single-molecule localization microscopy

This paper provides a protocol for implementing and calibrating spectroscopic single-molecule localization microscopy (sSMLM) and introduces a MATLAB package for 3D image reconstruction.

In vivo quantification of anterior and posterior chamber volumes in mice: implications for aqueous humor dynamics

This study measures anterior and posterior chamber volumes in mice, finding the anterior chamber constitutes 47% of total aqueous humor volume, significantly different from humans, and suggests previous inflow rate estimates may be overestimated.

Soft, 3D printed muscle ultrasound phantom with structurally tunable B-mode echo intensity

This paper develops 3D printed muscle ultrasound phantoms with tunable B-mode echo intensity to improve training and validation of ultrasound imaging.

3D Printing of Multiscale Scaffolds with Microtopography for Guiding Tissue Organization and Regeneration

This paper introduces a 3D printing technique to create multiscale scaffolds with microtopography to guide tissue organization and regeneration.

Experimental Parameters-Based Monte-Carlo Simulation of Single-Molecule Localization Microscopy of Nuclear Pore Complex to Evaluate Clustering Algorithms

The paper evaluates clustering algorithms for nuclear pore complex analysis using synthetic SMLM data generated by Monte-Carlo simulation.

RainbowSTORM: An open-source ImageJ plugin for spectroscopic single-molecule localization microscopy (sSMLM) data analysis and image reconstruction