Molecular Dynamics in the Ventral Tegmental Area during Chronic Pain-Induced Negative Affect
Cody C. Diezel, Lisa A. Majuta, Erfan Bahramnejad, Kelly L. Karlage, Jennifer L. Partin, Saniya M.D. Barbour, Ingrid L. Peterson, Matthew Flowers, Sophia T. von Hippel, Riley Haveman, Eva Villarroel-Candia, Isabella Villarroel, Paul R. Langlais, Tally M. Largent‐Milnes, Todd W. Vanderah, Arthur C. Riegel
This study investigates molecular changes in the ventral tegmental area of mice with chronic pain-induced negative affect, identifying sex-dependent Kv7.2 channel expression and endocannabinoid level alterations.
bioRxiv · Jul 1, 2025 · PreprintNeuroscience