Eric L. Garcia

The paper identifies SMN complex binding partners and reveals conserved connections to chaperone systems, linking chaperone dysfunction to ALS and SMA.

This study identifies hyperactivation of innate immune signaling as a consequence of SMN depletion in Drosophila SMA models, revealing a conserved regulatory role of the SMN complex.

This study compares transcriptomic changes in Drosophila snRNP biogenesis mutants to identify snRNP-dependent and Smn-specific RNA processing defects, finding differences between hypomorphic and complete loss-of-function Smn mutants.