Herpes simplex virus type 1 origin binding protein UL9 tethers and loops origin- and non-origin-DNA intra- and intermolecularly
Anita Felicitas Meier, Jan Vuckovic, Paul Girvan, Erin Cutts, Theodora Brophy, Benjamin Ambrose, David Rueda
This study investigates the role of HSV-1 UL9 in DNA looping and finds it does not efficiently loop oriS but can form large loops at non-origin sequences and tether intermolecular oriS DNA.
bioRxiv · Oct 30, 2024 · PreprintMicrobiology