Paul Girvan

This study visualizes human INO80's activity on DNA, showing it rapidly moves nucleosomes between chromatin barriers through directional reversal and boundary confinement.

The paper determines the distance-dependence of TMR self-quenching and bounds its dissociation timescale, validating it as an alternative to FRET for conformational change detection.

This study investigates the role of HSV-1 UL9 in DNA looping and finds it does not efficiently loop oriS but can form large loops at non-origin sequences and tether intermolecular oriS DNA.

This study investigates how TOP2 resolves DNA braids and shows cohesin inhibits its activity by preventing substrate access.