Jiawei Xing

Cache sensor domains of DUF3365/Tll0287 family bind covalent c-type heme through a CXXCH insertion; a signaling member behaves like an NO sensor, a stand-alone one like a redox protein.

LaVOUS models gene-expression dynamics along cell lineages, identifying lineage-associated changes in cancer, B cells, and brain development.

This study shows that ligand binding inhibits dimerization of the bacterial histidine kinase PdtaS, thereby repressing its activity and multi-ligand sensing.

This paper introduces BEAM, a Bayesian framework for inferring tissue migration histories in metastatic cancer from lineage tracing data, showing improved performance over existing methods.

This study identifies a chemoreceptor family in plant-associated bacteria that specifically responds to glycerol 3-phosphate, a plant stress signal, and shows its evolutionary origin and ecological relevance.

This study shows how a bacterial chemoreceptor evolved from a bimodular to a monomodular domain by losing one module, revealing that reducing complexity may be a common evolutionary trend in sensory domains.