Amanda M. Lauer

This study shows that hearing loss alters spatiotemporal neural activity patterns in the mouse auditory midbrain, specifically abolishing sideband suppression and tdOFF responses, which may contribute to tinnitus and hyperacusis.

The paper identifies FRMPD4 as a causal gene for X-linked non-syndromic hearing loss through genetic analysis and cross-species functional studies.

ABRA automates ABR waveform analysis using deep learning, achieving performance comparable to human experts while improving reproducibility and reducing analysis time.

This study investigates structural changes in auditory nerve synapses after moderate noise exposure, finding increased presynaptic vesicle density without changes in synaptic contact area or release sites.

The study investigates noise-induced vulnerability of low spontaneous rate type 1C spiral ganglion neuron synapses in C57Bl/6J mice using an LYPD1 reporter model and finds increased vulnerability of LYPD1-positive synapses.

This study shows that enhancing medial olivocochlear feedback protects against early noise-induced hearing damage in mice, with long-term auditory benefits.

This study investigates neural mechanisms of performance fluctuations in amnestic mice, finding that deficits are context-dependent and reversible, with preserved stimulus-action knowledge.

This study shows that big brown bats do not experience age-related hearing loss, as evidenced by comparable hearing thresholds and cochlear structure across age groups.

This study investigates how aging affects the response of mouse anteroventral cochlear nucleus neurons to sounds in quiet and noise, finding that threshold shifts decrease with age and spontaneous activity declines, suggesting deficits may arise from later auditory stages.

This study examines auditory function in 910KO mice, finding normal thresholds but altered startle responses and ABR amplitudes in noise, suggesting some auditory processing abnormalities.