Author

Özge Osmanoğlu

University of WürzburgORCID 0000-0002-7819-9262Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Signature Assays, Organisms & Methods

Click to filter · or open tag

Organism:human· 3 Approach:statistical model· 3 Research Focus:differential expression· 1 Organism:fungi (other)· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Thomas DandekariD· 4 shared Harald SchulzeiD· 2 shared Johannes BalkenholiD· 2 shared Juan Pablo PradaiD· 2 shared Katrin Gertrud HeinzeiD· 2 shared Martin Kaltdorf· 2 shared Andreas FriebeiD· 1 shared Axel A. BrakhageiD· 1 shared

Activity by Year

2021-2024 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

4 shared papersBioinformatics

Thomas DandekarORCID

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Thrombo-inflammation analyzed in a validated seven-layer platelet decision model: cellular decisions are tough problems fast and heuristically solved

Juan Pablo Prada, Johannes Balkenhol, Özge Osmanoğlu, Maral Afshar, Martin Kaltdorf, Sarah Hofmann, Sebastian von Mammen, Katrin Gertrud Heinze, Harald Schulze, Thomas Dandekar

The paper shows platelet signaling cascades are complex decision problems solved efficiently using heuristics, leading to fast responses but potential chronic inflammation under stress.

bioRxiv · Aug 2, 2024 · PreprintBioinformatics

Aspergillus fumigatus versus Genus Aspergillus: Conservation, adaptive evolution and specific virulence genes

Shishir Kumar Gupta, Mugdha Srivastava, Özge Osmanoğlu, Zhuofei Xu, Axel A. Brakhage, Thomas Dandekar

The paper identifies positively selected genes in Aspergillus fumigatus and related species, highlighting their roles in virulence, immune evasion, and adaptation.

Microorganisms · Sep 23, 2021Peer-reviewedBioinformatics

How biological cells including platelets and megakaryocytes decide complex problems fast but risky

Juan Pablo Prada, Johannes Balkenhol, Martin Kaltdorf, Özge Osmanoğlu, Martin Stoerkle, Katrin Gertrud Heinze, Georgi Manukjan, Harald Schulze, Thomas Dandekar

The paper examines how biological cells make fast, risky decisions that contribute to inflammation and cancer, drawing parallels to computational strategies for solving complex problems.

bioRxiv · Sep 10, 2021 · PreprintBioinformatics

cGMP signaling: probing antagonistic cyclic nucleotide platelet signals by modeling and experiment

Tim Breitenbach, Nils Englert, Özge Osmanoğlu, Natalia Rukoyatkina, Gaby Wangorsch, Andreas Friebe, Elke Butt, Robert Feil, Marcus T. Dittrich, Stepan P. Gambaryan, Thomas Dandekar

The paper develops and validates a model of cGMP signaling and VASP phosphorylation in platelets using data-driven approaches and experimental validation.

bioRxiv · Feb 1, 2021 · PreprintSystems Biology