This paper introduces 3DBonUS, a 3D bone printing method using ultrasound and microfluidic bioprinting to direct stem cell differentiation, showing increased osteogenic markers and mineralization.

bioRxiv · Nov 4, 2025 · PreprintBioengineering

Engineering a microfluidic-assisted 3D bioprinting approach for the hierarchical control deposition and compartmentalisation of graded bioinks

Federico Serpe, Lucia Iafrate, Marco Bastioli, Martina Marcotulli, Caterina Sanchini, Valeria de Turris, Michele D’Orazio, Biagio Palmisano, Arianna Mencattini, Eugenio Martinelli, Mara Riminucci, Carlo Massimo Casciola, Giancarlo Ruocco, Chiara Scognamiglio, Gianluca Cidonio

This paper introduces a microfluidic-assisted 3D bioprinting system that enables precise control over cell compartmentalization and material composition for creating interconnected, functional tissue constructs.

Biofabrication · Jul 23, 2025Peer-reviewedBioengineering

Aqueous two-phase bioinks for discrete packing and compartmentalisation of 3D bioprinted cells

Martina Marcotulli, Arianna Iacomino, Federico Serpe, Lucia Iafrate, Marco Bastioli, Giorgia Montalbano, Biagio Palmisano, Silvia Franco, Roberta Angelini, Alessandro Corsi, Mara Riminucci, Giancarlo Ruocco, Chiara Scognamiglio, Andrea Barbetta, Gianluca Cidonio

This paper develops ATPS bioinks for 3D bioprinting that enable precise cellular compartmentalization and tissue regeneration.

bioRxiv · Jun 27, 2025 · PreprintBioengineering