Coordinated regulation by lncRNAs results in tight lncRNA-target couplings
Hua‐Sheng Chiu, Sonal Somvanshi, Chung-Te Chang, Eric James de Bony de Lavergne, Zhaowen Wei, Chih-Hung Hsieh, Wim Trypsteen, Kathleen A. Scorsone, Ektaben Patel, Tien T. Tang, David B. Flint, Mohammad Javad Najaf Panah, Hyunjae Ryan Kim, Purva Rathi, Yan‐Hwa Wu Lee, , Pavel Sumazin
The paper identifies lncRNAs that coordinately regulate both transcription and post-transcriptional processing of their targets, showing tight coupling between lncRNA and target abundance, with implications for cancer gene regulation.
Cell Genomics · Jul 7, 2025Peer-reviewedBioinformatics