Transcriptional repression of Myc underlies AGO1's tumour suppressor function
Olga Zaytseva, Naomi C. Mitchell, Linna Guo, Owen J. Marshall, Linda M. Parsons, Ross D. Hannan, David Levens, Leonie M. Quinn
This study identifies AGO1 as a tumour suppressor in Drosophila that represses Myc transcription, inhibiting cell and tissue growth through direct transcriptional repression.
Development · Jun 1, 2020Peer-reviewedDevelopmental Biology