Christen Kerry Mirth

The paper measures age-related organ system decline in 19 Drosophila lines to show genetic variation in physiological decline patterns across genotypes.

The paper investigates how different dietary macronutrient conditions affect insulin-like peptide expression and developmental outcomes in Drosophila.

This study examines how combined thermal and nutritional stress affects larval thermotolerance and thermal plasticity in Drosophila melanogaster through experimental evolution.

This study shows dietary zinc and protein-to-carbohydrate ratio interact to regulate reproduction and lifespan in Drosophila, with Zn having effects comparable to macronutrient adjustments.

This study shows that low sterol diets in Drosophila melanogaster females lead to gut dysfunction and reduced lifespan.

This study shows that dietary zinc limitation in Drosophila affects reproduction without reducing lifespan, highlighting its role in resource allocation between fitness traits.

This study shows that GHSRs in the olfactory bulb link hunger to olfactory sensitivity, affecting food-seeking and metabolism in mice.

The paper shows that restricting individual amino acids, particularly isoleucine, in Drosophila melanogaster increases resistance to multiple stressors, including nicotine, oxidative stress, and cold shock.

This study shows GCN2-mediated autophagy allows Drosophila to use stored amino acids for somatic maintenance during dietary deprivation, extending lifespan.

The paper investigates how brain size and shape remain robust across environmental conditions by comparing growth dynamics in different Drosophila brain compartments.

This study shows ecdysone coordinates plastic growth and robust pattern in Drosophila wings by regulating growth via graded responses and patterning via threshold responses to nutritional changes.

The paper investigates how different essential amino acids affect egg production in Drosophila when depleted, finding that methionine and histidine have distinct impacts compared to other amino acids.

The study updates exome matching to account for protein size and expression, finding that differential gene expression between sexes does not improve fecundity, suggesting conserved amino acid proportions across taxa.

The paper shows that restricting a single amino acid in Drosophila increases survival during nicotine exposure through mTORC1 and GCN2 signaling pathways.

This study shows that insulin-like signaling coordinates Drosophila larval hemocyte number with body size, with reduced growth rate and impaired signaling leading to fewer hemocytes.

This study shows that NPFR in Drosophila prothoracic gland regulates development by modulating ecdysone production and insulin signaling, linking feeding behavior to developmental timing.

The paper identifies Torso-like as a secreted protein that regulates insulin signalling in Drosophila by modulating insulin-like peptide activity and developmental timing.