Qiang Lan

The CXCL10/CXCR3 axis is essential for sustaining immunological dormancy in breast cancer

This study identifies the CXCL10/CXCR3 axis as critical for maintaining immunological dormancy in breast cancer and shows its potential as a therapeutic target and prognostic marker in TNBC.

Directional cell motility facilitates side-branching in the mammary epithelium in a tension-sensitive manner

The paper investigates how directional cell motility drives side-branching in the mammary epithelium, showing that actomyosin network tension influences branching frequency.

On growth and form of the mammary gland: Mesenchyme instructs growth while epithelium directs branching

This study shows that mammary epithelium dictates branching patterns while mesenchyme controls growth and density during mammary gland development.

Stabilization of epithelial β-catenin compromises mammary cell fate acquisition and branching morphogenesis

This study shows that stabilizing β-catenin in mammary epithelium impairs branching morphogenesis and promotes epidermal differentiation over hair follicle fate.

Transcriptomic landscape of early hair follicle and epidermal development

The paper uses bulk and single-cell transcriptomics to study early hair follicle and epidermal development, identifying new cell populations and markers.

Exploring the principles of embryonic mammary gland branching morphogenesis

This study investigates branching morphogenesis in the embryonic mammary gland using ex vivo and in vivo techniques, revealing stochastic branching patterns and pathway-dependent regulation.