Yichang Jia

This paper develops an optimized optogenetic system using Acr proteins to regulate endogenous gene expression in Drosophila with improved light sensitivity.

This study identifies TRIM72's protective role in ALS through both cell-autonomous and non-cell-autonomous mechanisms, showing its therapeutic potential in animal models and human patients.

This study identifies TCF7L2 as a molecular switch in the midbrain that controls vocalization through transcriptional repression, showing its role in neuronal gene expression and synaptic transmission.