Dongsheng Fan

This study identifies TRIM72's protective role in ALS through both cell-autonomous and non-cell-autonomous mechanisms, showing its therapeutic potential in animal models and human patients.

This study uses Mendelian randomization to assess the causal effects of risk factors and drug targets on lacunar stroke, identifying potential drug repurposing opportunities.

The paper improves age prediction from DNA methylation using larger datasets, showing reduced error and limitations in capturing biological ageing variation.