Author

Ji He

Chinese Academy of SciencesORCID 0000-0002-1389-3544Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 1 Genetics· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Approach:statistical model· 2 Research Focus:benchmarking· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Assay:GWAS summary statistics· 1

Frequent Co-Authors

Dongsheng FaniD· 2 shared Alison D. MurrayiD· 1 shared Allan F. McRaeiD· 1 shared Andrew Mark McIntoshiD· 1 shared Anjali K. HendersiD· 1 shared Changqing ZengiD· 1 shared Chris HaleyiD· 1 shared Chunmu Yin· 1 shared

Activity by Year

2018-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

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2 shared papersNeuroscience

Dongsheng FanORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Title: Cell-autonomous and non-cell-autonomous effects of TRIM72 on ALS disease progression

Xue Zhang, Ji He, Ning Song, Xipeng Li, Weizhe Wang, Yueting Hu, Qing Li, Yiqing Hu, Chunmu Yin, Peng Zhao, Xinyi Jiang, Xuejiao Piao, Dawei Meng, Hongmei Cheng, Zhaohui Chen, , Yichang Jia

This study identifies TRIM72's protective role in ALS through both cell-autonomous and non-cell-autonomous mechanisms, showing its therapeutic potential in animal models and human patients.

bioRxiv · Jan 9, 2025 · PreprintNeuroscience

Searching across-cohort relatives in 54,092 GWAS samples via encrypted genotype regression

Qi-Xin Zhang, Tianzi Liu, Xinxin Guo, Jianxin Zhen, Mengyuan Yang, Saber Khederzadeh, Fang Xiao Zhou, Xiaotong Han, Qiwen Zheng, Peilin Jia, Xiaohu Ding, Mingguang He, Xin Zou, Jia-Kai Liao, Hongxin Zhang, , Guo‐Bo Chen

This paper introduces encG-reg, an encrypted genotype regression method that identifies relatives across cohorts without sharing raw data, achieving accuracy comparable to traditional methods.

PLoS Genetics · Jan 11, 2024Peer-reviewedGenetics

Improved prediction of chronological age from DNA methylation limits it as a biomarker of ageing

Qian Zhang, Costanza Ludovica Vallerga, Rosie May Walker, Tian Lin, Anjali K. Henders, Grant W. Montgomery, Ji He, Dongsheng Fan, Javed Fowdar, Martin Alexander Kennedy, Toni L. Pitcher, John Pearson, Glenda Margaret Halliday, John B. Kwok, Ian Bernard Hickie, , Peter M. Visscher

The paper improves age prediction from DNA methylation using larger datasets, showing reduced error and limitations in capturing biological ageing variation.

bioRxiv · Oct 28, 2018 · PreprintBioinformatics