Author
Research Institute of the McGill University Health CentreORCID 0000-0002-7770-0457Unclaimed ORCID profile · follow to get notified of new preprints
3 papers
Recent·Most cited
Brian Krug, Bo Hu, Haifeng Chen…·Chao Lü
The paper shows that H3K27me3 spreading regulates chromatin architecture and gene repression, with implications for cell fate and tumor development.
Tyler J. Reich, Paul A. Clark, Audrey Baguette…·Peter W. Lewis
The paper identifies SUZ12's nucleic acid-binding domain as critical for regulating PRC2 activity in H3 K27M gliomas, showing how it constrains enzymatic function and maintains targeted gene silencing.
Deepak Kumar Mishra, Shelli M. Morris, Dean Popovski…·Rachid Drissi
This study investigates the combination of DNA methyltransferase inhibitor decitabine and PD-1 inhibitor in high-risk pediatric brain tumor models, finding improved survival in some subtypes.