Nathan J. Brandt

Insights from sourdough redefine the domestication landscape of baker's yeast

This study analyzes sourdough yeast strains to reveal their domestication history, showing genetic distinctiveness from commercial strains and complex evolutionary influences from human cultural practices.

Temperature affects recombination rate plasticity and meiotic success between thermotolerant and cold tolerant yeast species

This study examines how temperature affects meiotic success and recombination rates in two yeast species with different thermal tolerances, finding temperature-dependent differences in sporulation and recombination.

Template switching during DNA replication is a prevalent source of adaptive gene amplification

The paper investigates how genomic architecture influences the formation and fitness of adaptive copy number variants (CNVs) in yeast, finding that template switching during DNA replication is a common mechanism for CNV generation.

Regulatory kinase genetic interaction profiles differ between environmental conditions and cellular states

The paper identifies differences in genetic interaction profiles of regulatory kinases between proliferative and quiescent yeast cells under various nutrient conditions.

Global analysis of gene expression dynamics identifies factors required for accelerated mRNA degradation

The paper identifies factors involved in accelerated mRNA degradation in yeast during a nitrogen upshift by combining genetic screening and molecular analysis.