Anastasia Baryshnikova

Platform-dependent effects of genetic variants on plasma APOL1

The paper identifies platform-dependent effects of APOL1 variants on plasma levels measured by different proteomic technologies.

Global analysis of the yeast knock-out phenome

The paper aggregates and analyzes phenotypic data from yeast knock-out screens to identify gene functions and relationships, revealing new biological insights.

A genome-scale yeast library with inducible expression of individual genes

The paper develops YETI, a yeast library with inducible gene expression, and shows low native expression can bias promoter-perturbing screens.

Regulatory kinase genetic interaction profiles differ between environmental conditions and cellular states

The paper identifies differences in genetic interaction profiles of regulatory kinases between proliferative and quiescent yeast cells under various nutrient conditions.

Yeast Genomic Screens Identify Kinesins as Potential Targets of the Pseudomonas syringae Type III Effector, HopZ1a

The paper identifies HopZ1a, a T3SE from Pseudomonas syringae, as an acetyltransferase that targets plant kinesins to disrupt microtubule networks through yeast genetic and interaction screens.

Comparative analysis of protein abundance studies to quantify the Saccharomyces cerevisiae proteome

This study normalizes and compares 19 yeast proteomic datasets to estimate absolute protein abundance and assess measurement variability across stress conditions.

Spatial Analysis of Functional Enrichment (SAFE) in Large Biological Networks

The paper introduces SAFE, a method to annotate biological networks with functional enrichments, and demonstrates its application to yeast genetic interaction networks.

Functional Annotation of Chemical Libraries across Diverse Biological Processes

This study develops a yeast-based chemical-genetic screening system to annotate compound functionality across biological processes and identifies compounds with dual modes of action.