Author

Linzhen Kong

University of Oxford

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Genomics· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Assay:DNA methylation· 3 Approach:experimental assay· 3 Organism:human· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Organism:mouse· 1 Research Focus:variant calling· 1

Frequent Co-Authors

Chun‐Xiao SongiD· 3 shared Haiqi XuiD· 2 shared Jingfei ChengiD· 2 shared Xiufei CheniD· 2 shared Aleema IqbaliD· 1 shared Alfredo CastellóiD· 1 shared Azman Embarc BuhiD· 1 shared Dagny Sanden Døskeland· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 28 mutual co-author links

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3 shared papersBiochemistry

Chun‐Xiao SongORCID

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3 papers

Recent·Most cited

mBACS enhances pseudouridine profiling through efficient and robust chemical conversion

Feng Feng, Giuseppina Pisignano, Linzhen Kong, Thomas Grimes, Paul E. Brennan, Chun‐Xiao Song

mBACS improves pseudouridine profiling with higher conversion efficiency and lower false positives, revealing new sites and functional insights into tRNA modifications.

bioRxiv · Sep 9, 2026 · PreprintBiochemistry

Direct, bisulfite-free 5mC and 5hmC sequencing at single-cell resolution

Xiufei Chen, Jingfei Cheng, Linzhen Kong, Xiao Shu, Haiqi Xu, Masato Inoue, Marion Silvana Fernández-Berrocal, Dagny Sanden Døskeland, Magnar Bjørås, Shivan Sivakumar, Yibin Liu, Jing Ye, Chun‐Xiao Song

This paper introduces two single-cell sequencing methods for detecting 5mC and 5hmC, showing increased 5hmC in aging mouse hippocampus.

Genome biology · Aug 18, 2025Peer-reviewedGenomics

Absolute quantitative and base-resolution sequencing reveals comprehensive landscape of pseudouridine across the human transcriptome

Haiqi Xu, Linzhen Kong, Jingfei Cheng, Khatoun Al Moussawi, Xiufei Chen, Aleema Iqbal, Peter A. C. Wing, James M. Harris, Senko Tsukuda, Azman Embarc Buh, Guifeng Wei, Alfredo Castelló, Skirmantas Kriaučionis, Jane A. McKeating, Xin Lü, Chun‐Xiao Song

This paper introduces BACS, a method for single-base resolution pseudouridine quantification, and identifies {Psi} sites in human RNA and viral transcripts.

Nature Methods · Sep 30, 2024Peer-reviewedMolecular Biology