Author
Michael Okun
University of LeicesterORCID 0000-0002-7795-5513Unclaimed ORCID profile · follow to get notified of new preprints
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Biology Disciplines
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2016-2026 · peak 2/yrCo-Author Collaboration Network
10 top collaborators · 29 mutual co-author links10 papers
Recent·Most cited
Disassociating cerebral vasomotion from low frequency spontaneous neurovascular coupling
Runchong Wang, Priya Patel, Luke W. Boorman, Michael Okun, Clare Howarth, Jason Berwick
This study investigates cerebral vasomotion in anaesthetised rats, finding it driven by the arterial tree and largely independent of neural activity.
Scientific Reports · Dec 18, 2025Peer-reviewedNeuroscience
Multi-day Neuron Tracking in High Density Electrophysiology Recordings using EMD
Augustine Xiaoran Yuan, Jennifer I. Colonell, Anna Lebedeva, Michael Okun, Adam S. Charles, T.D. Harris
This paper introduces a neuron tracking method using non-rigid alignment of spike sorted clusters to identify the same neurons across multiple days in high density electrophysiology recordings, achieving an 84% average recovery rate.
eLife · Dec 12, 2023Peer-reviewedNeuroscience
Stretching and squeezing of neuronal log firing rate distribution by psychedelic and intrinsic brain state transitions
Bradley Dearnley, Martynas Dervinis, Melissa Shaw, Michael Okun
This study examines how psychedelic drugs and intrinsic brain state transitions affect neuronal firing rate distributions in mice, revealing a common pattern of stretching and squeezing in log-rate distributions across different brain states.
bioRxiv · Aug 22, 2021 · PreprintNeuroscience
Neuropixels 2.0: A miniaturized high-density probe for stable, long-term brain recordings
Nicholas A. Steinmetz, Çağatay Aydın, Anna Lebedeva, Michael Okun, Marius Pachitariu, Marius Bauža, Maxime Beau, Jai Bhagat, Claudia Böhm, Martijn Broux, Susu Chen, Jennifer I. Colonell, Richard J. Gardner, Bill Karsh, Fabian Kloosterman, , T.D. Harris
The paper introduces Neuropixels 2.0, a high-density probe for long-term brain recordings, and demonstrates its stability across months in multiple labs and species.
Science · Apr 15, 2021Peer-reviewedNeuroscience
Equations governing dynamics of excitation and inhibition in the mouse corticothalamic network
I-Chun Lin, Michael Okun, Matteo Carandini, Kenneth D. Harris
The paper shows that mean-field models of cortical dynamics require inclusion of thalamic interactions to accurately predict responses to optogenetic stimulation in awake mice.
bioRxiv · Jun 3, 2020 · PreprintNeuroscience
Neural basis of learning guided by sensory confidence and reward value
Armin Lak, Michael Okun, Morgane M. Moss, Harsha Gurnani, Karolina Farrell, Miles J. Wells, Charu Bai Reddy, Ádám Kepecs, Kenneth D Harris, Matteo Carandini
This study investigates how mice integrate sensory confidence and reward value in decision-making and learning, revealing distinct roles for frontal and dopamine neurons.
bioRxiv · Apr 13, 2019 · PreprintNeuroscience
Distinct structure of cortical population activity on fast and infraslow timescales
Michael Okun, Nicholas A. Steinmetz, Armin Lak, Martynas Dervinis, Kenneth D Harris
The paper analyzes cortical spiking dynamics across fast and infraslow timescales in mice, revealing distinct coupling patterns between individual neurons and population activity.
Cerebral Cortex · Jan 28, 2019Peer-reviewedNeuroscience
Inhibitory control of shared variability in cortical networks
Carsen Stringer, Marius Pachitariu, Michael Okun, Peter Bartho, Kenneth Harris, Peter Latham, Maneesh Sahani, Nicholas Lesica
This study develops a deterministic spiking network model to analyze multi-neuron recordings and shows that feedback inhibition controls noise correlations in cortical networks.
bioRxiv · Jul 16, 2016Neuroscience
Long term recordings with immobile silicon probes in the mouse cortex
Michael Okun, Matteo Carandini, Kenneth D Harris
This study shows that immobile silicon probes can provide stable, long-term neuronal recordings in mice for several months without microdrives.
PLOS ONE · Mar 9, 2016Peer-reviewedNeuroscience