Miles J. Wells

Mice infer stimulus-side priors from recent choices; prior signals are decodable pre-stimulus in 24.0% to 30.2% of 242 brain regions, including early visual and motor areas.

The paper presents a brain-wide neural activity map from 621,733 neurons across 139 mice performing a decision-making task, showing how neural activity encodes task variables across brain regions.

The paper shows that mice with ASD-related mutations exhibit similar computational and neural anomalies in prior updating during decision-making.

This study evaluates the reproducibility of electrophysiological measurements across ten labs using standardized protocols and finds that variability in electrode targeting and statistical methods affects reproducibility.

The paper introduces two public websites for exploring large-scale electrophysiology data from the International Brain Laboratory, enabling cross-platform access to behavioral trials and neuronal data.

The paper describes a modular data architecture for a neuroscience collaboration, enabling data contribution, access, and analysis across multiple labs.

This paper develops a standardized task for measuring decision-making in mice, showing reproducible results across multiple laboratories and providing a public dataset and tools.

The paper shows that mouse frontal cortex combines auditory and visual evidence additively during learning, mirroring behavior, and that this combination is impaired by optogenetic inactivation.

This study shows that spatial representations in V1 and CA1 are correlated and influenced by non-visual factors like distance traveled and theta oscillations.

Rigbox is an open-source software toolbox for behavioral neuroscience experiments, offering modular design, hardware I/O, data synchronization, and stimulus presentation.

This study investigates how mice integrate sensory confidence and reward value in decision-making and learning, revealing distinct roles for frontal and dopamine neurons.

This paper introduces high-yield methods for two-alternative visual psychophysics in head-fixed mice, showing rapid learning and accurate psychometric curves.