Roger Wellington-Oguri

The paper designs compact RNA sensors for complex functions of multiple inputs using crowdsourced designs and an algorithm, achieving applications like tuberculosis diagnosis.

This study uses community science and experimental screening to design mutant ribosomes with improved protein synthesis and cell growth in vitro and vivo.

This study develops PERSIST-seq and In-line-seq to optimize mRNA stability and translation, finding that in-cell stability is more critical than ribosome load for protein output.

A crowdsourced RNA design approach discovers efficient, reversible molecular sensors that couple small molecule inputs to protein binding and fluorogenic outputs.