Author

Mugdha Srivastava

University of WürzburgORCID 0000-0002-7449-9911Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 1 Immunology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 3 Research Focus:gene regulatory network inference· 3 Assay:bulk RNA-seq· 2 Approach:experimental assay· 2 Approach:statistical model· 2 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Organism:fungi (other)· 1

Frequent Co-Authors

Alexander G. NickeliD· 1 shared Anja KarlstaedtiD· 1 shared Anna-Lena Bettenhausen· 1 shared Axel A. BrakhageiD· 1 shared Christoph MaackiD· 1 shared Claudia SommeriD· 1 shared DiyaaElDin AshouriD· 1 shared Ebram Tharwat Melika· 1 shared

Activity by Year

2021-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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1 shared paperImmunology

Alexander G. NickelORCID

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Author profile →

3 papers

Recent·Most cited

Interferon gamma signaling drives cardiac metabolic rewiring

Ebram Tharwat Melika, DiyaaElDin Ashour, Kyoungmin Kim, Alexander G. Nickel, Paula-Anahi Arias-Loza, Xinyu Chen, Panagiota Arampatzi, Mugdha Srivastava, Martin Väth, Edécio Cunha‐Neto, Michaela Kühn, Georg Gasteiger, Ulrich Hofmann, Takahiro Higuchi, Christoph Maack, , Gustavo Campos Ramos

This study shows that IFN-gamma signaling in cardiomyocytes causes metabolic changes in the heart, including increased glucose uptake and reduced oxidative phosphorylation, which resemble changes in aging and heart failure.

bioRxiv · Aug 31, 2025 · PreprintImmunology

Neuronal toxicity and recovery from early bortezomib-induced neuropathy: targeting the blood nerve barrier but not the dorsal root ganglion

Mariam Sobhy Atalla, Anna-Lena Bettenhausen, Julius M. Verse, Nadine Cebulla, Susanne M. Krug, Reine‐Solange Sauer, Mugdha Srivastava, Thorsten Bischler, Jeremy Tsung-Chieh Chen, Klaus Martin Kortüm, Robert J. Kittel, Claudia Sommer, Heike Lydia Rittner

This study investigates bortezomib-induced neuropathy in rats and patients, showing that early toxicity targets the blood nerve barrier, which can recover through upregulation of netrin-1.

bioRxiv · May 31, 2024 · PreprintNeuroscience

Aspergillus fumigatus versus Genus Aspergillus: Conservation, adaptive evolution and specific virulence genes

Shishir Kumar Gupta, Mugdha Srivastava, Özge Osmanoğlu, Zhuofei Xu, Axel A. Brakhage, Thomas Dandekar

The paper identifies positively selected genes in Aspergillus fumigatus and related species, highlighting their roles in virulence, immune evasion, and adaptation.

Microorganisms · Sep 23, 2021Peer-reviewedBioinformatics