Maithé Arruda-Carvalho

C57BL/6 Mouse Substrain Differences in the Ontogeny of Auditory Fear

This study compares the development of auditory fear memory in two C57BL/6 mouse substrains, finding differences in the timing of fear persistence, recovery, and renewal.

Maturation of Hippocampus-Medial Prefrontal Cortex Projections Defines a Pathway-Specific Sensitive Period for Cognitive Flexibility

This study examines the development of hippocampus-mPFC projections in mice, finding that juvenile inhibition of specific pathways affects adult cognitive flexibility in a sex- and pathway-specific manner.

Dorsal peduncular cortex activity modulates affective behavior and fear extinction in mice

This study shows that activating the dorsal peduncular cortex (DP/DTT) in mice increases anxiety-like behavior and affects fear extinction, suggesting a role in emotional regulation.

Intermediate CA1 is Required for Object-in-Place Recognition Memory in Mice

This paper establishes that intermediate CA1 hippocampal subregion is required for object-in-place recognition memory in mice, using chemogenetic inhibition and behavioral testing.

Maturation of Nucleus Accumbens Synaptic Transmission Signals a Critical Period for the Rescue of Social Deficits in a Mouse Model of Autism Spectrum Disorder

This study examines age-dependent changes in synaptic transmission in the nucleus accumbens of ASD mouse models and finds that early intervention with rapamycin rescues social deficits.