Author

Minh‐Tam Pham

Johns Hopkins UniversityORCID 0000-0002-7833-628XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Genomics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Research Focus:cancer & tumor microenvironment· 1 Assay:DNA methylation· 1 Research Focus:variant calling· 1

Frequent Co-Authors

Srinivasan YegnasubramanianiD· 2 shared Ajay M. VaghasiaiD· 1 shared Alok Mishra· 1 shared Angelo Michael De MarzoiD· 1 shared Anthony C. O'DonnelliD· 1 shared Archana Rachakonda· 1 shared David M. EsopiiD· 1 shared Glenn HaukiD· 1 shared

Activity by Year

2022-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersCancer Biology

Srinivasan YegnasubramanianORCID

Mutual co-authors in cluster

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2 papers

Recent·Most cited

Triptolide sensitizes cancer cells to nucleoside DNA methyltransferase inhibitors through inhibition of DCTPP1-mediated cell-intrinsic resistance

Jianyong Liu, Qing-Li He, Jianya Zhou, Ajay M. Vaghasia, Roshan V. Chikarmane, Glenn Hauk, Archana Rachakonda, Nicole Castagna, Ruchama Chaya Steinberg, Minh‐Tam Pham, Jordan M. Gregg, Alok Mishra, Yuhan Yang, Talha Anwar, Roy Elias, , Srinivasan Yegnasubramanian

This paper identifies triptolide as a compound that enhances the effectiveness of DNMTi by inhibiting DCTPP1, overcoming resistance in cancer cells.

Nature Communications · Aug 26, 2026Peer-reviewedCancer Biology

Achieving single nucleotide sensitivity in direct hybridization genome imaging

Yanbo Wang, Wayne Taylor Cottle, Haobo Wang, Momčilo M. Gavrilov, Roger S. Zou, Minh‐Tam Pham, Srinivasan Yegnasubramanian, Scott Bailey, Taekjip Ha

This paper introduces sgGOLDFISH, a method for single-nucleotide sensitivity in direct hybridization genome imaging, and demonstrates its application in identifying and localizing point mutations in progeroid fibroblasts.

Nature Communications · Dec 15, 2022Peer-reviewedGenomics