Alternating Access of a Neurotransmitter:Sodium Symporter Bacterial Homolog Determined from AlphaFold2 Ensembles and DEER Spectroscopy
Alexandra C. Schwartz, Richard A. Stein, Eva Gil‐Iturbe, Matthias Quick, Hassane S. Mchaourab
This paper uses AlphaFold2 and DEER spectroscopy to study the conformational dynamics of MhsT, revealing energy landscapes and environmental effects on transporter function.
Proceedings of the National Academy of Sciences · Sep 20, 2024Peer-reviewedBiophysics