Catherine Chen

This study identifies white adipose tissue lipolysis and circulating fatty acids as key mediators of metabolic tolerance to infection, showing improved survival in sepsis with beta3-adrenergic agonists.

This study identifies a genetic variant linked to impaired complement regulation that worsens chronic lung allograft dysfunction-free survival by promoting B cell activation and donor-specific antibodies.

This study shows that the ATG16L1 genetic variant impairs macrophage metabolism, leading to lung transplant rejection, and suggests targeting glycolysis could prevent chronic lung allograft dysfunction.

The paper identifies distinct target-specific mechanisms that stabilize synaptic strength at pre- and post-synaptic compartments in Drosophila neuromuscular junctions.

This study identifies the sleep gene insomniac as essential for retrograde homeostatic signaling by ubiquitinating targets at postsynaptic densities in Drosophila.