Author

Alexander Leach

Georgia State UniversityORCID 0000-0002-7875-9258Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Organism:mouse· 1 Organism:non-human primate· 1 Organism:rat· 1

Frequent Co-Authors

Alexander L. GreningeriD· 2 shared Dariia VyshenskaiD· 2 shared Richard Karl PlemperiD· 2 shared Robert M. CoxiD· 2 shared Amalia Anne CruziD· 1 shared Andres MeritsiD· 1 shared Carolin M. LieberiD· 1 shared Claire RuckeliD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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2 shared papersMicrobiology

Alexander L. GreningerORCID

Mutual co-authors in cluster

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2 papers

Recent·Most cited

Developmental candidate GHP-88310/EIDD-3608 with high tolerability and oral efficacy in measles and respiratory paramyxovirus models

Carolin M. Lieber, Josef D. Wolf, Mugunthan Govindarajan, Jeong-Joong Yoon, Zachary M. Sticher, Claire Ruckel, Alexander Leach, Lauren A. Harrison, Dariia Vyshenska, Amalia Anne Cruz, Meghan K. Andrews, Rebecca E. Krueger, Robert M. Cox, George R. Painter, Alexander L. Greninger, , Richard Karl Plemper

This paper develops a new antiviral compound, GHP-88310, showing high tolerability and oral efficacy against measles and respiratory paramyxoviruses in animal models.

Science Advances · May 22, 2026Peer-reviewedMicrobiology

Identification and Characterization of Novel Chikungunya Virus Polymerase Inhibitors

Peiqi Yin, Ryan Boyce, Sainan Wang, Michael R. Sirrine, Alexander Leach, Dillon Chu, Dariia Vyshenska, Zafer Şahin, Jenny Wong, Tahirah Moore, Devin Shane M. Lewis, Stephen C. Pelly, Dennis Liotta, Andres Merits, Alexander L. Greninger, , Robert M. Cox

This study identifies novel small-molecule inhibitors of Chikungunya virus replication through high-throughput screening and characterizes their mechanism of action and resistance profiles.

Journal of Virology · May 19, 2026Peer-reviewedMolecular Biology