Author

George R. Painter

Emory UniversityORCID 0000-0002-9803-8095Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Microbiology· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 3 Research Focus:drug response / drug discovery· 2 Research Focus:host-pathogen & immune response· 1 Organism:non-human primate· 1 Organism:rat· 1

Frequent Co-Authors

Alexander L. GreningeriD· 3 shared Dariia VyshenskaiD· 3 shared Amalia Anne CruziD· 2 shared Carolin M. LieberiD· 2 shared Michael G. NatchusiD· 2 shared Rebecca E. KruegeriD· 2 shared Richard Karl PlemperiD· 2 shared Robert M. CoxiD· 2 shared

Activity by Year

2026-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 42 mutual co-author links

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3 shared papersMicrobiology

Alexander L. GreningerORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

EIDD-3525 is a broad-spectrum antiviral against alphavirus infection that targets the nsP4 RNA-dependent RNA polymerase

Peiqi Yin, Shweta Choudhary, Sainan Wang, Bennett Davenport, Phong Truong, Zachary M. Sticher, Rebecca E. Krueger, Amalia Anne Cruz, McKenzie Smith, Alexander A. Kolykhalov, Dariia Vyshenska, Alexander L. Greninger, Shuli Mao, Michael G. Natchus, George R. Painter, , Thomas E. Morrison

This study identifies EIDD-3525 as a broad-spectrum antiviral against alphaviruses that inhibits RNA replication by targeting the nsP4 polymerase.

bioRxiv · Sep 28, 2026 · PreprintMicrobiology

Developmental candidate GHP-88310/EIDD-3608 with high tolerability and oral efficacy in measles and respiratory paramyxovirus models

Carolin M. Lieber, Josef D. Wolf, Mugunthan Govindarajan, Jeong-Joong Yoon, Zachary M. Sticher, Claire Ruckel, Alexander Leach, Lauren A. Harrison, Dariia Vyshenska, Amalia Anne Cruz, Meghan K. Andrews, Rebecca E. Krueger, Robert M. Cox, George R. Painter, Alexander L. Greninger, , Richard Karl Plemper

This paper develops a new antiviral compound, GHP-88310, showing high tolerability and oral efficacy against measles and respiratory paramyxoviruses in animal models.

Science Advances · May 22, 2026Peer-reviewedMicrobiology

Impact of Mutations Affecting 4'-Fluorouridine Susceptibility on Fitness and Treatment Outcomes for Venezuelan Equine Encephalitis Virus

Jenny Wong, Tahirah Moore, Devin Lewis, Carolin M. Lieber, Dariia Vyshenska, Elizabeth B. Sobolik, Sarah Zimmermann, George R. Painter, Richard Karl Plemper, Alexander L. Greninger, Robert M. Cox

This study identifies mutations in VEEV nsP4 that reduce susceptibility to 4-FlU, shows these mutations do not fully prevent 4-FlU's therapeutic effect in mice, and highlights its potential as an antiviral for alphavirus encephalitis.

Journal of Virology · Jan 15, 2026Peer-reviewedMicrobiology