Author

Huan Souza

Boston UniversityORCID 0000-0002-7881-2821Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:scRNA-seq· 2 Research Focus:benchmarking· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Approach:machine learning (classical)· 1

Frequent Co-Authors

Pankaj MehtaiD· 2 shared Andrea Brigitta AlberiD· 1 shared Ansley S. ConcholaiD· 1 shared Brigitte N. GompertsiD· 1 shared Chandani SeniD· 1 shared Dakota L. JonesiD· 1 shared Darrell N. KottoniD· 1 shared Diya Gopal· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersBioinformatics

Pankaj MehtaORCID

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2 papers

Recent·Most cited

BioinformaticsbioRxivPreprintFeb 13, 2026

Simple models outperform single-cell foundation models on downstream benchmarks

Huan Souza, Pankaj Mehta

This paper shows simple linear models can achieve state-of-the-art results on single-cell RNA sequencing benchmarks, outperforming complex foundation models in out-of-distribution tasks.

1 citation

scRNA-seqmachine learning (classical)

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Molecular BiologybioRxivPreprintJan 31, 2026

Bidirectional fibrogenic cross-talk revealed in a human iPSC-derived epithelial-mesenchymal co-culture model of pulmonary fibrosis

Andrea Brigitta Alber, George Kwong, Vishal K Gupta…·Darrell N. Kotton

The paper establishes a human iPSC-derived co-culture model of pulmonary fibrosis that reveals bidirectional fibrogenic epithelial-mesenchymal crosstalk and identifies potential druggable pathways.

2 citations

humanscRNA-seq

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