David M. Sturgill

U2AF regulates the translation and localization of nuclear-encoded mitochondrial mRNAs

This study identifies U2AF's role in regulating mitochondrial function by controlling translation and localization of nuclear-encoded mitochondrial mRNAs, with implications for disease.

Predictive Prioritization of Enhancers Associated with Pancreas Disease Risk

The paper develops a method to prioritize enhancers linked to pancreas disease risk by integrating chromatin interactions, machine learning, and single-cell perturbation assays.

TET-catalyzed 5-carboxylcytosine promotes CTCF binding to suboptimal sequences genome-wide

The paper shows that 5caC enhances CTCF binding to suboptimal sequences and identifies ~13,000 new CTCF binding sites in a cellular model with high 5caC levels.

Independence Between Pre-mRNA Splicing And De Novo DNA Methylation In An Isogenic Minigene Resource

The paper investigates the relationship between pre-mRNA splicing and DNA methylation using an isogenic minigene resource and finds they are independent.