Benjamin T. Donovan

This study identifies U2AF's role in regulating mitochondrial function by controlling translation and localization of nuclear-encoded mitochondrial mRNAs, with implications for disease.

The paper applies a kinetic proofreading model to elucidate how transient U2AF binding leads to high fidelity splice site selection.

This study uses single-molecule imaging to show that Gal4 dwell time determines transcriptional burst size in yeast, with nucleosomes reducing dwell time and affecting transcriptional bursting kinetics.

This study investigates how budding yeast pioneer transcription factors bind and dissociate from nucleosomal DNA, showing they compensate for reduced binding by increasing dwell time, similar to human pioneer factors.