Daniel R. Neill

This study identifies mutations in ilvD, encoding a BCAA biosynthesis protein, as beneficial for pneumococcal survival in blood but detrimental for nasopharyngeal colonization.

This study identifies a thermosensing master regulator in Streptococcus pneumoniae that mediates the switch from commensal to pathogenic state through temperature-dependent regulation of surface adhesin expression.

This study identifies sputum proteomic signatures linked to FEV1 and QoL changes in cystic fibrosis trials, revealing distinct physiological mechanisms.