Molecular BiologybioRxivPreprint
Identification of a P62-TIF-IA axis that drives nucleolar fusion and the senescence associated secretory phenotype
Hazel C. Thoms, Tyler S. Brant, Katie Duckett…·Lesley A. Stark
This study identifies a p62-TIF-IA axis that drives nucleolar fusion and the senescence-associated secretory phenotype (SASP) through ATM-mediated disruption of autophagic degradation.
DOI 10.1101/2023.12.05.570133