François Agnès

This study creates a single-nucleus RNA-seq atlas of Astyanax mexicanus embryogenesis, revealing tissue-specific transcriptional tempo shifts and developmental microevolution mechanisms.

This study examines RPE morphogenesis in fish, showing anisotropic stretching and nuclear scaling during optic cup formation, with differences between cave and surface-dwelling morphs.

The paper identifies cis-regulatory changes driving developmental gene expression differences between surface and blind cavefish morphs, with rx3 regulation showing both cis-autonomous and non-autonomous mechanisms.

The paper creates a 3D molecular map of the cavefish neural plate to study eyefield organization and its borders in vertebrates, revealing structural and molecular differences between wild-type and cavefish embryos.