Jorge Torres‐Paz

A cellular atlas of Astyanax mexicanus embryogenesis reveals principles of developmental microevolution

This study creates a single-nucleus RNA-seq atlas of Astyanax mexicanus embryogenesis, revealing tissue-specific transcriptional tempo shifts and developmental microevolution mechanisms.

The retinal pigment epithelium undergoes anisotropic stretching and nuclear size scaling during optic cup morphogenesis in a fish model.

This study examines RPE morphogenesis in fish, showing anisotropic stretching and nuclear scaling during optic cup formation, with differences between cave and surface-dwelling morphs.

Evolution of the regulation of developmental gene expression in blind Mexican cavefish

The paper identifies cis-regulatory changes driving developmental gene expression differences between surface and blind cavefish morphs, with rx3 regulation showing both cis-autonomous and non-autonomous mechanisms.

A 3D molecular map of the cavefish neural plate illuminates eyefield organization and its borders in vertebrates

The paper creates a 3D molecular map of the cavefish neural plate to study eyefield organization and its borders in vertebrates, revealing structural and molecular differences between wild-type and cavefish embryos.

The olfactory organ is a unique site for resident neutrophils in the brain

This study identifies the olfactory organ as the only brain region containing resident neutrophils and reveals its unique lymphatic vasculature and immune response to damage.

Pescoids and chimeras to probe early evo-devo in the fish Astyanax mexicanus

The paper describes methods to study early developmental processes in Astyanax mexicanus using gastruloids and chimeric embryos to investigate cell fate decisions and developmental programs.

Maternally-regulated gastrulation as a source of variation contributing to cavefish forebrain evolution

The paper identifies maternal-regulated gastrulation heterochronies in cavefish that contribute to forebrain evolution by altering gene expression patterns during early development.