Sergi Roig‐Puiggros

This study creates a single-nucleus RNA-seq atlas of Astyanax mexicanus embryogenesis, revealing tissue-specific transcriptional tempo shifts and developmental microevolution mechanisms.

This study shows that post-mitotic cortical neurons retain birthdate-dependent differentiation potential, with early-born neurons maintaining a broader repertoire than late-born neurons.

This study compares prenatal cortical development in two rodents, showing that major developmental milestones occur prenatally in Acomys, challenging the view that postnatal experience is essential for early brain maturation.

The paper investigates how environmental factors influence neocortical neuron fate and diversity through in vivo and in vitro experiments, showing population-specific responses and the importance of extracellular context.

This study shows that heterotopic neurons in EmlJ knockout mice retain functional properties similar to neocortical neurons despite their abnormal location.

The paper identifies two distinct astrocyte lineages in the mouse neocortex using single-cell RNA sequencing and TrackerSeq, revealing their developmental origins and regulatory mechanisms.

This study shows that loss of floor plate Netrin-1 disrupts corticospinal tract midline crossing in mice, causing mirror movements similar to human congenital conditions.