Author

Lara Grande

Centro de Investigación Médica AplicadaORCID 0000-0002-7922-8731Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioengineering· 1

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:organoid / primary culture· 1

Frequent Co-Authors

Carlos Ortíz-de-SolórzanoiD· 1 shared Ioritz Sorzabal-BellidoiD· 1 shared Iván Cortés‐DomíngueziD· 1 shared Maider EsparzaiD· 1 shared Mariano Ponz‐SarviséiD· 1 shared Pedro Castillo· 1 shared Shruthi NarayananiD· 1 shared Silvestre VicentiD· 1 shared

Activity by Year

2024-2024 · peak 1/yr

Co-Author Collaboration Network

9 top collaborators · 36 mutual co-author links

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1 shared paperBioengineering

Carlos Ortíz-de-SolórzanoORCID

Mutual co-authors in cluster

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1 paper

Recent·Most cited

Quantitative evaluation of the role of the microenvironment in the phenotype, metabolism, and drug resistance of PDAC tumor organoids

Ioritz Sorzabal-Bellido, Xabier Morales, Iván Cortés‐Domínguez, Maider Esparza, Lara Grande, Pedro Castillo, Shruthi Narayanan, Mariano Ponz‐Sarvisé, Silvestre Vicent, Carlos Ortíz-de-Solórzano

This study evaluates how scaffold composition affects PDAC organoid phenotype, metabolism, and drug resistance, finding that collagen-Matrigel mixtures best mimic invasive tumors.

bioRxiv · Dec 31, 2024 · PreprintBioengineering