Author

Shruthi Narayanan

Clinica Universidad de NavarraORCID 0000-0003-1375-3637Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioengineering· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 2 Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Organism:human· 2 Research Focus:cell type annotation· 1 Research Focus:host-pathogen & immune response· 1 Assay:metagenomics· 1 Organism:mouse· 1

Frequent Co-Authors

Mariano Ponz‐SarviséiD· 2 shared Silvestre VicentiD· 2 shared Adrienne D. CoxiD· 1 shared Andrew M. WatersiD· 1 shared Bjoern PapkeiD· 1 shared Carlos Ortíz-de-SolórzanoiD· 1 shared Channing J. DeriD· 1 shared Christine SersiD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 38 mutual co-author links

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2 shared papersCancer Biology

Mariano Ponz‐SarviséORCID

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2 papers

Recent·Most cited

Cancer BiologybioRxivPreprintAug 11, 2026

Concurrent AXL inhibition enhances RAS and ERK inhibitor efficacy in KRAS-mutant pancreatic and lung cancer

Yan Ming Ching, Shruthi Narayanan, Jeffrey A. Klomp…·Bjoern Papke

This study shows that combining AXL inhibition with RAS or ERK inhibitors enhances efficacy in KRAS-mutant cancers by overcoming resistance mechanisms.

1 citation

humanmouse

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BioengineeringbioRxivPreprintDec 31, 2024

Quantitative evaluation of the role of the microenvironment in the phenotype, metabolism, and drug resistance of PDAC tumor organoids

Ioritz Sorzabal-Bellido, Xabier Morales, Iván Cortés‐Domínguez…·Carlos Ortíz-de-Solórzano

This study evaluates how scaffold composition affects PDAC organoid phenotype, metabolism, and drug resistance, finding that collagen-Matrigel mixtures best mimic invasive tumors.

DOI 10.1101/2024.12.31.630904

humanorganoid / primary culture

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