Author

Basel A. Karim

Stanford UniversityORCID 0000-0002-7928-0433Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Research Focus:cell signaling & trafficking· 1 Assay:ChIP-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

Briana Howard· 1 shared Gabriela AlexeiD· 1 shared Giulia DiGiovanniiD· 1 shared Kenneth N. RossiD· 1 shared Kimberly StegmaieriD· 1 shared Michael J. BondiD· 1 shared Nathanael S. GrayiD· 1 shared Roman C. SarottiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

Briana Howard

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1 paper

Recent·Most cited

Rewiring the fusion oncoprotein EWS/FLI1 in Ewing sarcoma with bivalent small molecules

Michael J. Bond, Ryan P. Golden, Giulia DiGiovanni, Briana Howard, Roman C. Sarott, Basel A. Karim, Sai P. Gourisankar, Gabriela Alexe, Kenneth N. Ross, Nathanael S. Gray, Kimberly Stegmaier

This study develops a bivalent small molecule, EB-TCIP, that relocalizes EWS/FLI1 to induce BCL6 target genes, demonstrating a strategy to target fusion oncoproteins in Ewing sarcoma.

bioRxiv · Mar 14, 2025 · PreprintCancer Biology