Author

Michael J. Bond

Boston Children's HospitalORCID 0000-0001-9552-4525Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:proteomics· 2 Research Focus:cell signaling & trafficking· 1 Assay:ChIP-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Kimberly StegmaieriD· 2 shared Ananthan SadagopaniD· 1 shared Anurag Sodhi· 1 shared Basel A. KarimiD· 1 shared Benjamin L. EbertiD· 1 shared Briana Howard· 1 shared Cary N. WeissiD· 1 shared Eric S. FischeriD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersBiochemistry

Kimberly StegmaierORCID

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2 papers

Recent·Most cited

An epigenetic bifunctional that toggles between transactivation and repression

Ananthan Sadagopan, Maximilian Carson, Eriks J. Zamurs, Shanivi Srikonda, Cary N. Weiss, Michael J. Bond, Anurag Sodhi, Katherine A. Donovan, Julia K Ryan, Eric S. Fischer, Kimberly Stegmaier, Srinivas Raghavan Viswanathan, Benjamin L. Ebert, William J. Gibson

This paper identifies a bifunctional small molecule that can induce both transactivation and repression of gene expression depending on cellular context.

bioRxiv · Mar 20, 2026 · PreprintBiochemistry

Rewiring the fusion oncoprotein EWS/FLI1 in Ewing sarcoma with bivalent small molecules

Michael J. Bond, Ryan P. Golden, Giulia DiGiovanni, Briana Howard, Roman C. Sarott, Basel A. Karim, Sai P. Gourisankar, Gabriela Alexe, Kenneth N. Ross, Nathanael S. Gray, Kimberly Stegmaier

This study develops a bivalent small molecule, EB-TCIP, that relocalizes EWS/FLI1 to induce BCL6 target genes, demonstrating a strategy to target fusion oncoproteins in Ewing sarcoma.

bioRxiv · Mar 14, 2025 · PreprintCancer Biology