Author

Ryan P. Golden

Stanford MedicineORCID 0009-0004-7113-007XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Research Focus:cell signaling & trafficking· 1 Assay:ChIP-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:deep learning· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

Nathanael S. GrayiD· 2 shared Antara ChakravartyiD· 1 shared Basel A. KarimiD· 1 shared Briana Howard· 1 shared Eric S. FischeriD· 1 shared Gabriela AlexeiD· 1 shared Giulia DiGiovanniiD· 1 shared Guangyan Du· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersCancer Biology

Nathanael S. GrayORCID

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2 papers

Recent·Most cited

Rewiring the fusion oncoprotein EWS/FLI1 in Ewing sarcoma with bivalent small molecules

Michael J. Bond, Ryan P. Golden, Giulia DiGiovanni, Briana Howard, Roman C. Sarott, Basel A. Karim, Sai P. Gourisankar, Gabriela Alexe, Kenneth N. Ross, Nathanael S. Gray, Kimberly Stegmaier

This study develops a bivalent small molecule, EB-TCIP, that relocalizes EWS/FLI1 to induce BCL6 target genes, demonstrating a strategy to target fusion oncoproteins in Ewing sarcoma.

bioRxiv · Mar 14, 2025 · PreprintCancer Biology

Discovery of Potent Degraders of the Dengue Virus Envelope Protein

Zhengnian Li, Han‐Yuan Liu, Zhixiang He, Antara Chakravarty, Ryan P. Golden, Zixuan Jiang, Inchul You, Hong Yue, Katherine A. Donovan, Guangyan Du, Jianwei Che, Jason Tse, Isaac Che, Wenchao Lu, Eric S. Fischer, , Priscilla L. Yang

This study develops small molecule degraders of the dengue virus envelope protein, demonstrating their ability to induce proteosome-mediated degradation and providing a foundation for antiviral drug development.

Advanced Science · Aug 15, 2024Peer-reviewedBiochemistry