Author

Alexandra M. Pike

Johns Hopkins UniversityORCID 0000-0002-7928-2455Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Organism:mouse· 1

Frequent Co-Authors

Carla J. ConnellyiD· 2 shared Carol W. GreideriD· 2 shared Margaret A. StrongiD· 2 shared John Paul T. OuyangiD· 1 shared Stella S. LeeiD· 1 shared Steven WangiD· 1 shared

Activity by Year

2017-2019 · peak 1/yr

Co-Author Collaboration Network

6 top collaborators · 13 mutual co-author links

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2 shared papersMolecular Biology

Carla J. ConnellyORCID

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2 papers

Recent·Most cited

Molecular BiologyMolecular and Cellular BiologyPeer-reviewedAug 5, 2019

TIN2 functions with TPP1/POT1 to stimulate telomerase processivity

Alexandra M. Pike, Margaret A. Strong, John Paul T. Ouyang…·Carol W. Greider

This study identifies a new TIN2 isoform, TIN2M, and shows that all TIN2 isoforms enhance telomerase processivity beyond TPP1/POT1, suggesting TIN2 is a functional component of the TPP1/POT1 complex.

55 citationstop 3%

humanexperimental assay

𝕏 PostBluesky

Molecular BiologyNucleic Acids ResearchPeer-reviewedJun 22, 2017

BRD4 inhibitors block telomere elongation

Steven Wang, Alexandra M. Pike, Stella S. Lee…·Carol W. Greider

This study identifies BRD4 as a telomere length regulator and shows that BRD4 inhibitors block telomere elongation in mouse and human cells.

45 citations

𝕏 PostBluesky