John Paul T. Ouyang

The paper shows that two parallel sRNA amplification loops in C. elegans mediate RNAi inheritance by targeting nascent and mature transcripts through distinct mechanisms.

The paper shows that P granules in C. elegans germ cells prevent RNA interference genes from being silenced by piRNAs, maintaining their expression.

This study identifies a new TIN2 isoform, TIN2M, and shows that all TIN2 isoforms enhance telomerase processivity beyond TPP1/POT1, suggesting TIN2 is a functional component of the TPP1/POT1 complex.