NeuroscienceScientific ReportsPeer-reviewed
KAT8 compound inhibition inhibits the initial steps of PINK1-dependant mitophagy
Capucine de Talhouët, Noemí Esteras, Marc P. M. Soutar…·Hélène Plun‐Favreau
This study shows that KAT8 inhibition via MG149 blocks PINK1-dependent mitophagy initiation but promotes mitochondrial delivery to lysosomes without toxins.
10 citations