Author

Tianjiao Yuan

Changping LaboratoryORCID 0000-0002-7949-4490Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:benchmarking· 2 Research Focus:database / resource· 2 Assay:DNA methylation· 2 Organism:mouse· 2 Research Focus:software / tool· 2 Research Focus:variant calling· 2 Research Focus:cell type annotation· 1

Frequent Co-Authors

Yali BaiiD· 3 shared Yunlong CaoiD· 3 shared Aicui Zhang· 2 shared Liuhao ReniD· 2 shared Liyang SongiD· 2 shared Xiaoliang Sunney XieiD· 2 shared Yinghui ZhengiD· 2 shared Yueyang LiuiD· 2 shared

Activity by Year

2023-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 43 mutual co-author links

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3 shared papersGenetics

Yali BaiORCID

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3 papers

Recent·Most cited

GeneticsbioRxivPreprintJul 20, 2026

cf-Cabernet: Nick Repair Prior to End Repair Preserves Endogenous DNA Methylation Information in Cell-Free DNA Methylation Sequencing

Tianjiao Yuan, Yali Bai, Liyang Song…·Y J Cao

cf-Cabernet improves cfDNA methylation sequencing by repairing nicks before end repair, preserving methylation information and outperforming standard methods.

DOI 10.64898/2026.07.14.738208

DNA methylationexperimental assay

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GeneticsbioRxivPreprintMay 29, 2025

Single-cell Characterization of DNA Hydroxymethylation of the Mouse Brain During Aging

Yali Bai, Tianjiao Yuan, Liuhao Ren…·Yunlong Cao

The paper introduces Joint-Cabernet, a single-cell platform for profiling 5hmC and 5mC, and applies it to mouse brain nuclei to study DNA hydroxymethylation changes with aging.

3 citations

mousescRNA-seq

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GenomicsProceedings of the National Academy of SciencesPeer-reviewedNov 27, 2023

Single-cell bisulfite-free 5mC and 5hmC sequencing with high sensitivity and scalability

Yunlong Cao, Yali Bai, Tianjiao Yuan…·Xiaoliang Sunney Xie

The paper introduces Cabernet, a bisulfite-free single-cell method for high-resolution 5mC and 5hmC profiling, revealing epigenetic dynamics in mouse embryos and demonstrating scalability for complex tissues.

43 citationstop 4%

mouseDNA methylation

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