Janine Sophie Kemming

KIR Expression Defines a Transcriptionally Distinct CD8+ T-cell Population that Confounds Antigen-Specific T-cell Detection

This paper identifies KIR-mediated pHLA-C binding as a confounder in T-cell analysis and provides a method to distinguish it from TCR-specific binding.

Hybrid quantum-classical de novo design of MHC-binding peptides

This paper introduces a hybrid quantum-classical pipeline for designing MHC-binding peptides, showing that quantum-derived priors improve the yield of strong binders, especially for understudied HLA alleles.

Autoantigen-specific CD8+ T-cell signature in Rheumatoid Arthritis

This study identifies HLA class I-restricted CD8+ T-cell epitopes in RA and shows how citrullination affects antigen recognition and T-cell clonotype stability.