Mohammad Kadivar

This paper identifies KIR-mediated pHLA-C binding as a confounder in T-cell analysis and provides a method to distinguish it from TCR-specific binding.

This study shows that Ag-Neo2/15 scaffolds expand antigen-specific T cells with enhanced cytotoxicity and reduced dysfunctionality compared to Ag-IL2/21 scaffolds.

This study identifies impaired HPV-specific CD8 T cell recognition and a suppressive immune microenvironment in cervical cancer, highlighting the need for enhanced T cell responses and immune suppression targeting.

ITRAP2 improves TCR-pMHC pairing accuracy by reducing noise and cross-contamination in single-cell data, outperforming existing methods on both in-house and public datasets.

This study identifies antigen-specific CD8+ T-cell responses linked to disease severity in SARS-CoV-2 infection, showing functional impairment and recognition bias.