Author

Richard J. Spelman

Livestock Improvement CorporationORCID 0000-0002-7968-1392Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genetics· 1 Genomics· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 3 Assay:bulk RNA-seq· 2 Research Focus:differential expression· 1 Research Focus:eQTL / molecular QTL mapping· 1 Research Focus:GWAS / association mapping· 1 Assay:GWAS summary statistics· 1

Frequent Co-Authors

Kathryn TipladyiD· 3 shared Mathew D. LittlejohniD· 3 shared Stephen R. DavisiD· 3 shared Thomas JohnsoniD· 3 shared Thomas LopdelliD· 3 shared B.L. HarrisiD· 2 shared Christine CouldreyiD· 2 shared Russell G. SnelliD· 2 shared

Activity by Year

2019-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 43 mutual co-author links

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3 shared papersGenetics

Kathryn TipladyORCID

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3 papers

Recent·Most cited

Non-additive QTL mapping of lactation traits in 124,000 sequence-imputed cattle reveals novel recessive loci

Edwardo Reynolds, Thomas Lopdell, Yu Wang, Kathryn Tiplady, Chad Harland, Thomas Johnson, Catherine Neeley, Katie Carnie, Richard G. Sherlock, Christine Couldrey, Stephen R. Davis, B.L. Harris, Richard J. Spelman, Dorian J. Garrick, Mathew D. Littlejohn

The paper identifies novel recessive loci affecting lactation traits in cattle using non-additive QTL mapping on 124,000 sequence-imputed cows, revealing differences in genetic architecture between milk yield and composition traits.

Genetics Selection Evolution · Jan 24, 2022Peer-reviewedGenetics

A new mechanism for a familiar mutation - bovine DGAT1 K232A modulates gene expression through multi-junction exon splice enhancement

Tania Fink, Thomas Lopdell, Kathryn Tiplady, Renée R. Handley, Thomas Johnson, Richard J. Spelman, Stephen R. Davis, Russell G. Snell, Mathew D. Littlejohn

The paper re-examines the mechanism of the DGAT1 K232A mutation in bovine milk production, showing it modulates gene expression through splicing enhancement.

BMC Genomics · Aug 26, 2020Peer-reviewedMolecular Biology

Multiple QTL underlie milk phenotypes at the CSF2RB locus

Thomas Lopdell, Kathryn Tiplady, Christine Couldrey, Thomas Johnson, Michael Keehan, Stephen R. Davis, B.L. Harris, Richard J. Spelman, Russell G. Snell, Mathew D. Littlejohn

The paper identifies multiple QTL at the CSF2RB locus associated with milk yield and composition traits in dairy cattle and explores their genetic and molecular mechanisms.

Genetics Selection Evolution · Jan 24, 2019Peer-reviewedGenomics